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Fig. 4 | Cancer Cell International

Fig. 4

From: Long non-coding RNA UCA1 promotes breast cancer by upregulating PTP1B expression via inhibiting miR-206

Fig. 4

UCA1 is capable of elevating PTP1B expression through inhibiting miR-206. a Bioinformatics prediction of the interaction between UCA1 and miR-206 through complementary base-pairs was shown. The mutant sequence of UCA1 is indicated. b Luciferase activities of pGL-PTP1B were analyzed by luciferase reporter gene assay in miR-206 and/or UCA1 (or UCA1-206-mut) transfected MCF-7 cells. c In miR-206 and/or UCA1 (or UCA1-206-mut) treated cells, PTP1B expression was assessed by Western blot. **p < 0.01 and no significance (NS), Student’s t-test

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Cancer Cell International

ISSN: 1475-2867

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