Fig. 4

Tiam1 is involved in the activation of Rac1 by TUFT1 in TNBC cell lines. a, b TUFT1-overexpressing MDA-MB-231 cells treated with or without NSC23766. a Rac1-GTP expression was examined by western blotting (n = 3). b Cell migration was monitored by transwell assay (n = 3). Results are presented as mean ± SD. The statistical significance was assessed by student’s t-test; **p < 0.01