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Table 2 Results of subgroup meta-analysis

From: Prognostic impact of platelet-to-lymphocyte ratio on diffuse large B-cell lymphoma: a meta-analysis

Characteristics No. of studies No. of patients Effects model HR (95% CI) p Heterogeneity
I2 (%) Ph
OS
 All 8 1931 Random 1.73 (1.29–2.31) < 0.001 58.6 0.018
Ethnicity
 Caucasian 2 618 Fixed 1.32 (0.95–1.84) 0.103 0 0.624
 Asian 6 1313 Random 1.95 (1.34–2.84) < 0.001 64.2 0.016
Sample size
 ≤ 200 4 494 Fixed 1.88 (1.32–2.67) < 0.001 31.7 0.222
 > 200 4 1437 Random 1.63 (1.09–2.45) 0.018 75 0.007
Cut-off value
 ≤ 150 3 584 Random 1.74 (0.92–3.28) 0.088 73.5 0.023
 > 150 5 1347 Random 1.76 (1.25–2.49) 0.001 55 0.064
PFS
 All 7 1416 Random 0.85 (0.57–1.27) 0.438 77.8 < 0.001
Ethnicity
 Caucasian 1 103 0.57 (0.3–1.09) 0.091
 Asian 6 1313 Random 0.91 (0.58–1.41) 0.66 80 < 0.001
Sample size
 ≤ 200 4 494 Random 0.67 (0.34–1.34) 0.26 74.7 0.008
 > 200 3 922 Random 1.08 (0.73–1.62) 0.69 72.8 0.025
Cut-off value
 ≤ 150 3 584 Random 0.62 (0.32–1.21) 0.161 80.1 0.007
 > 150 4 832 Random 1.12 (0.76–1.65) 0.58 54.7 0.085