Prognostic impact of platelet-to-lymphocyte ratio on diffuse large B-cell lymphoma: a meta-analysis

Table 2 Results of subgroup meta-analysis

Characteristics	No. of studies	No. of patients	Effects model	HR (95% CI)	p	Heterogeneity
Characteristics	No. of studies	No. of patients	Effects model	HR (95% CI)	p	I² (%)	Ph
OS
All	8	1931	Random	1.73 (1.29–2.31)	< 0.001	58.6	0.018
Ethnicity
Caucasian	2	618	Fixed	1.32 (0.95–1.84)	0.103	0	0.624
Asian	6	1313	Random	1.95 (1.34–2.84)	< 0.001	64.2	0.016
Sample size
≤ 200	4	494	Fixed	1.88 (1.32–2.67)	< 0.001	31.7	0.222
> 200	4	1437	Random	1.63 (1.09–2.45)	0.018	75	0.007
Cut-off value
≤ 150	3	584	Random	1.74 (0.92–3.28)	0.088	73.5	0.023
> 150	5	1347	Random	1.76 (1.25–2.49)	0.001	55	0.064
PFS
All	7	1416	Random	0.85 (0.57–1.27)	0.438	77.8	< 0.001
Ethnicity
Caucasian	1	103	–	0.57 (0.3–1.09)	0.091	–	–
Asian	6	1313	Random	0.91 (0.58–1.41)	0.66	80	< 0.001
Sample size
≤ 200	4	494	Random	0.67 (0.34–1.34)	0.26	74.7	0.008
> 200	3	922	Random	1.08 (0.73–1.62)	0.69	72.8	0.025
Cut-off value
≤ 150	3	584	Random	0.62 (0.32–1.21)	0.161	80.1	0.007
> 150	4	832	Random	1.12 (0.76–1.65)	0.58	54.7	0.085

ISSN: 1475-2867