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Table 3 Correlation of PLR and clinical factors

From: Prognostic impact of platelet-to-lymphocyte ratio on diffuse large B-cell lymphoma: a meta-analysis

Characteristics No. of studies No. of patients Effects model OR (95% CI) p Heterogeneity
I2 (%) Ph
B symptoms (yes vs no) 5 803 Random 2.27 (1.29–3.98) 0.004 60.2 0.039
LDH (> normal vs < normal) 5 803 Fixed 2.76 (2.05–3.72) < 0.001 0 0.703
Stage (III–IV vs I–II) 5 803 Fixed 2.22 (1.66–2.98) < 0.001 21.1 0.28
Gender (male vs female) 5 803 Fixed 0.9 (0.67–1.19) 0.447 3.8 0.385
Age (≥ 60 vs < 60) 5 803 Fixed 0.91 (0.69–1.21) 0.527 0 0.875
ECOG PS (≥ 2 vs < 2) 4 494 Fixed 1.71 (1.09–2.69) 0.019 0 0.745
Cell of origin (GCB vs non-GCB) 2 491 Fixed 0.94 (0.65–1.38) 0.765 0 0.740
  1. LDH: lactate dehydrogenase; ECOG PS: Eastern Cooperative Oncology Group performance status; GCB: germinal center B cell