From: Prognostic impact of platelet-to-lymphocyte ratio on diffuse large B-cell lymphoma: a meta-analysis
Characteristics | No. of studies | No. of patients | Effects model | OR (95% CI) | p | Heterogeneity | |
---|---|---|---|---|---|---|---|
I2 (%) | Ph | ||||||
B symptoms (yes vs no) | 5 | 803 | Random | 2.27 (1.29–3.98) | 0.004 | 60.2 | 0.039 |
LDH (> normal vs < normal) | 5 | 803 | Fixed | 2.76 (2.05–3.72) | < 0.001 | 0 | 0.703 |
Stage (III–IV vs I–II) | 5 | 803 | Fixed | 2.22 (1.66–2.98) | < 0.001 | 21.1 | 0.28 |
Gender (male vs female) | 5 | 803 | Fixed | 0.9 (0.67–1.19) | 0.447 | 3.8 | 0.385 |
Age (≥ 60 vs < 60) | 5 | 803 | Fixed | 0.91 (0.69–1.21) | 0.527 | 0 | 0.875 |
ECOG PS (≥ 2 vs < 2) | 4 | 494 | Fixed | 1.71 (1.09–2.69) | 0.019 | 0 | 0.745 |
Cell of origin (GCB vs non-GCB) | 2 | 491 | Fixed | 0.94 (0.65–1.38) | 0.765 | 0 | 0.740 |