The miR-141/neuropilin-1 axis is associated with the clinicopathology and contributes to the growth and metastasis of pancreatic cancer

Table 1 Correlation between NRP-1 expression and clinicopathological parameters in patients with pancreatic cancer

Parameters	Total (n = 57)	NRP-1 expression level		P value
Parameters	Total (n = 57)	Low (n = 34)	High (n = 23)	P value
Gender				0.862
Male	31	19	12
Female	26	15	11
Age (year)				0.511
< 60	35	21	14
≥ 60	22	13	9
Tumor grade				0.015
Well	7	6	1
Moderate	47	26	21
Poor	3	1	2
Tumor location				0.396
Head	43	28	15
Body/tail	14	6	8
Tumor size				0.224
< 40 mm	36	22	14
≥ 40 mm	21	12	9
T stage				0.109
T1–T2	7	3	4
T3	28	17	11
T4	23	14	9
Lymph metastasis				0.002
Negative	16	14	2
Positive	41	20	21
AJCC staging				0.044
I + II	26	20	6
III + IV	31	14	17
CA19-9 (U/L)				0.087
< 37	22	18	4
≥ 37	35	16	19

P value was estimated by a Mann–Whitney test
AJCC American Joint Committee on Cancer, NRP-1 neuropilin-1, CA19-9 carbohydrate antigen19-9

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