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Table 1 Correlation between NRP-1 expression and clinicopathological parameters in patients with pancreatic cancer

From: The miR-141/neuropilin-1 axis is associated with the clinicopathology and contributes to the growth and metastasis of pancreatic cancer

Parameters Total (n = 57) NRP-1 expression level P value
Low (n = 34) High (n = 23)
Gender 0.862
 Male 31 19 12  
 Female 26 15 11  
Age (year) 0.511
 < 60 35 21 14  
 ≥ 60 22 13 9  
Tumor grade 0.015
 Well 7 6 1  
 Moderate 47 26 21  
 Poor 3 1 2  
Tumor location 0.396
 Head 43 28 15  
 Body/tail 14 6 8  
Tumor size 0.224
 < 40 mm 36 22 14  
 ≥ 40 mm 21 12 9  
T stage 0.109
 T1–T2 7 3 4  
 T3 28 17 11  
 T4 23 14 9  
Lymph metastasis 0.002
 Negative 16 14 2  
 Positive 41 20 21  
AJCC staging 0.044
 I + II 26 20 6  
 III + IV 31 14 17  
CA19-9 (U/L) 0.087
 < 37 22 18 4  
 ≥ 37 35 16 19  
  1. P value was estimated by a Mann–Whitney test
  2. AJCC American Joint Committee on Cancer, NRP-1 neuropilin-1, CA19-9 carbohydrate antigen19-9