Fig. 4

a Distribution of the HGS risk score and its correlation to recurrence in the training, TCGA cohort and meta-validation cohort, with risk scores as the continuous variable for individual patients. The DFS and recurrence in the different hypoxia risk groups of training cohort (b), TCGA cohort (e) and meta-validation cohort (h). Kaplan–Meier curves comparing survival of patients with low or high hypoxia risk in training cohort (c), TCGA cohort (f) and meta-validation cohort (i). P-values were calculated using log-rank tests and HR is short for hazard ratio