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Table 3 C-index for hypoxic risk compared with Oncotype DX in three cohorts

From: A signature of hypoxia-related factors reveals functional dysregulation and robustly predicts clinical outcomes in stage I/II colorectal cancer patients

Cohorts HGS Oncotype DX
C-index 95% CI C-index 95% CI
CIT/GSE39582 (training) 0.80 0.70–0.90 0.65 0.53–0.77
TCGA (validation) 0.70 0.55–0.85 0.61 0.44–0.77
Meta-validation 0.68 0.55–0.80 0.73 0.64–0.83