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Table 3 C-index for hypoxic risk compared with Oncotype DX in three cohorts

From: A signature of hypoxia-related factors reveals functional dysregulation and robustly predicts clinical outcomes in stage I/II colorectal cancer patients

Cohorts

HGS

Oncotype DX

C-index

95% CI

C-index

95% CI

CIT/GSE39582 (training)

0.80

0.70–0.90

0.65

0.53–0.77

TCGA (validation)

0.70

0.55–0.85

0.61

0.44–0.77

Meta-validation

0.68

0.55–0.80

0.73

0.64–0.83