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Fig. 5 | Cancer Cell International

Fig. 5

From: Long noncoding RNA DLX6-AS1 promotes neuroblastoma progression by regulating miR-107/BDNF pathway

Fig. 5

Knockdown of DLX6-AS1 inhibits tumor growth in vivo. a Relative expression levels of DLX6-AS1 in SKNSH cells stably transfected with shNC or DLX6-AS1 by qRTPCR. b Tumor volume was measured in shNC group and shDLX6-AS1 group at indicated times. c The weight of dissected tumors in shDLX6-AS1 group was lower than that in shNC group. The expression of d DLX6-AS1 and e miR-107 in dissected tumor tissues from shNC group and shDLX6-AS1 group were determined by qRT-PCR. f The BDNF, GAP43 and NF-200 protein expression of dissected tumor tissues were determined by western blot. g Survival analysis showing the overall survival of mice treated with shNC or shDLX6-AS1 SH-SY5Y cells. **p < 0.01 and ***p < 0.001

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