Skip to main content

Table 2 The implication of increased CD146 in Cancer

From: CD146 T cells in lung cancer: its function, detection, and clinical implications as a biomarker and therapeutic target

Cancer type Implications References
Lung cancer Poor prognosis [12, 13, 102,103,104]
Hepatocellular carcinoma Promotes metastasis and predicts poor prognosis [105, 106]
Epithelial ovarian cancer Poor prognosis [107]
Breast cancer Elevated epithelial-mesenchymal transition [108, 109]
Leiomyosarcoma Prognostic factor [110]
Esophageal squamous cell carcinoma Poor prognosis [111]
Gallbladder adenocarcinoma Progression, metastasis, and poor-prognosis [98]
Colorectal cancer Poor prognosis [112]
Gastric cancer Poor prognosis [113]
Clear cell renal cell carcinoma Elevated reoccurrence [114]
Melanoma Elevated metastasis and poor prognosis [115]
Hematological malignancies Elevated tumorigenesis [116]
Peripheral nerve tumors Modulator of malignant transformation [117]
Parotid carcinoma Elevated progression and invasion [118]
Non-small cell lung cancer Poor prognosis [12]
Infantile haemangioma Elevated progression [119]
Adenoid cystic carcinoma Elevated progression [120]
Malignant pleural mesothelioma Poor prognosis [121]
Pancreatic cancer Poor Prognosis and cancer progression [14]
Cervical cancer Dissemination and metastasis [123]
Endometrium Dissemination and metastasis [123]
Prostate cancer Poor prognosis [122]