Cancer Cell International

Table 2 Univariate and multivariate analysis between 22 subpopulations of TIICs and survival in experiment group

From: Identification of 3 subpopulations of tumor-infiltrating immune cells for malignant transformation of low-grade glioma

TIICs	Univariate analysis			Multivariate analysis
TIICs	HR	p-value	95% CI	HR	B	p-value	95% CI
B cells naive	0.709	0.158	0.440–1.143
B cells memory	0.068	1.558	0.968–2.507
Plasma cells	0.594	0.028*	0.371–0.949	0	− 7.889	0.181	0–39.380
T cells CD8	1.071	0.778	0.664–1.730
T cells CD4 naive	0.229	0.144	0.032–1.652
T cells CD4 memory resting	0.736	0.208	0.456–1.187
T cells CD4 memory activated	1.875	0.121	0.848–4.145
T cells follicular helper	2.641	< 0.001*	1.585–4.400	1.69E+06	14.339	0.046*	1.298–2.196E+12
T cells regulatory (Tregs)	0.979	0.929	0.613–1.563
T cells gamma delta	1.304	0.354	0.743–2.289
NK cells resting	1.653	0.036*	1.027–2.660	0	− 9.67	0.099	0–6.150
NK cells activated	0.498	0.003*	0.310–0.800	0	− 22.69	< 0.001*	0–Inf
Monocytes	0.367	< 0.001*	0.223–0.603	0.141	− 1.959	0.259	0.005–4.228
Macrophages M0	4.103	< 0.001*	2.500–6.733	10.527	2.354	0.018*	1.501–73.813
Macrophages M1	1.763	0.019*	1.089–2.852	2157.986	7.677	0.072	0.503–9.261E+6
Macrophages M2	0.768	0.27	0.481–1.227
Dendritic cells resting	2.017	0.004*	1.243–3.274	0	− 8.748	0.423	0–3.094E+5
Dendritic cells activated	0.486	0.04*	0.241–0.983	0	− 62.875	0.233	0–3.495E+17
Mast cells resting	0.928	0.821	0.486–1.774
Mast cells activated	0.76	0.248	0.477–1.210
Eosinophils	0.678	0.106	0.424–1.086
Neutrophils	1.03	0.904	0.641–1.655

*Statistically significant

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