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Table 2 Univariate and multivariate analysis between 22 subpopulations of TIICs and survival in experiment group

From: Identification of 3 subpopulations of tumor-infiltrating immune cells for malignant transformation of low-grade glioma

TIICs Univariate analysis Multivariate analysis
HR p-value 95% CI HR B p-value 95% CI
B cells naive 0.709 0.158 0.440–1.143     
B cells memory 0.068 1.558 0.968–2.507     
Plasma cells 0.594 0.028* 0.371–0.949 0 − 7.889 0.181 0–39.380
T cells CD8 1.071 0.778 0.664–1.730     
T cells CD4 naive 0.229 0.144 0.032–1.652     
T cells CD4 memory resting 0.736 0.208 0.456–1.187     
T cells CD4 memory activated 1.875 0.121 0.848–4.145     
T cells follicular helper 2.641 <0.001* 1.585–4.400 1.69E+06 14.339 0.046* 1.298–2.196E+12
T cells regulatory (Tregs) 0.979 0.929 0.613–1.563     
T cells gamma delta 1.304 0.354 0.743–2.289     
NK cells resting 1.653 0.036* 1.027–2.660 0 − 9.67 0.099 0–6.150
NK cells activated 0.498 0.003* 0.310–0.800 0 − 22.69 <0.001* 0–Inf
Monocytes 0.367 <0.001* 0.223–0.603 0.141 − 1.959 0.259 0.005–4.228
Macrophages M0 4.103 <0.001* 2.500–6.733 10.527 2.354 0.018* 1.501–73.813
Macrophages M1 1.763 0.019* 1.089–2.852 2157.986 7.677 0.072 0.503–9.261E+6
Macrophages M2 0.768 0.27 0.481–1.227     
Dendritic cells resting 2.017 0.004* 1.243–3.274 0 − 8.748 0.423 0–3.094E+5
Dendritic cells activated 0.486 0.04* 0.241–0.983 0 − 62.875 0.233 0–3.495E+17
Mast cells resting 0.928 0.821 0.486–1.774     
Mast cells activated 0.76 0.248 0.477–1.210     
Eosinophils 0.678 0.106 0.424–1.086     
Neutrophils 1.03 0.904 0.641–1.655     
  1. *Statistically significant