Table 4 GO enrichment and KEGG pathway analysis results with grouped all samples into high- and low-IRS group
GO/KEGG | Pathway ID | Pathway description | False discovery rate |
|---|---|---|---|
GOBP | GO.0022617 | Extracellular matrix disassembly | 2.24E−05 |
GO.0030198 | Extracellular matrix organization | 5.75E−05 | |
GO.0040012 | Regulation of locomotion | 7.51E−05 | |
GO.0030334 | Regulation of cell migration | 0.0002 | |
GO.0001503 | Ossification | 0.000601 | |
GOCC | GO.0005615 | Extracellular space | 1.16E−10 |
GO.0044421 | Extracellular region part | 3.19E−06 | |
GO.0005576 | Extracellular region | 9.92E−06 | |
GO.0005578 | Proteinaceous extracellular matrix | 0.000868 | |
GO.0044420 | Extracellular matrix component | 0.000868 | |
GO.0005793 | Endoplasmic reticulum-Golgi intermediate compartment | 0.00291 | |
GOMF | GO.0005518 | Collagen binding | 0.00543 |
GO.0031730 | CCR5 chemokine receptor binding | 0.0436 | |
KEGG | 4512 | ECM-receptor interaction | 0.000163 |
4151 | PI3K-Akt signaling pathway | 0.00375 | |
4510 | Focal adhesion | 0.00375 | |
910 | Nitrogen metabolism | 0.0339 |