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Fig. 2 | Cancer Cell International

Fig. 2

From: Inactivation of the Wnt/β-catenin signaling pathway underlies inhibitory role of microRNA-129-5p in epithelial–mesenchymal transition and angiogenesis of prostate cancer by targeting ZIC2

Fig. 2

miR-129-5p is poorly-expressed while ZIC2, Wnt3a and β-catenin are highly-expressed in PCa tissues. a The miR-129-5p expression and mRNA expression of ZIC2, Wnt3a and β-catenin in PCa tissues and adjacent normal tissues determined by RT-qPCR. Data are summarized as mean ± standard deviation and compared with paired t test (n = 60). b Immunohistochemical staining of Wnt3a and β-catenin in PCa tissues and adjacent normal tissues, in which brown or yellowish staining represents positive cells. c The statistical analysis of b. *p < 0.05 vs. the adjacent normal tissues. Positive rates are count data and were compared with the Chi square test

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