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Fig. 7 | Cancer Cell International

Fig. 7

From: Inactivation of the Wnt/β-catenin signaling pathway underlies inhibitory role of microRNA-129-5p in epithelial–mesenchymal transition and angiogenesis of prostate cancer by targeting ZIC2

Fig. 7

Angiogenesis of PCa cells is blocked by overexpressed miR-129-5p or down-regulated ZIC2. DU-145 cells were treated with miR-129-5p mimic, miR-129-5p inhibitor or/and si-ZIC2. a The angiogenesis in each group; b the angiogenesis indexes in each group; c the protein expression of VEGF and CD31 in each group; d the statistical analysis of c. *p < 0.05 vs. the blank and NC groups. The data are summarized as mean ± standard deviation. The experiment was repeated three times and the data were compared using the one-way analysis of variance. VEGF vascular endothelial growth factor, GAPDH glyceraldehyde-3-phosphate dehydrogenase

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