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Fig. 1 | Cancer Cell International

Fig. 1

From: Histone methyltransferase SUV39H2 regulates cell growth and chemosensitivity in glioma via regulation of hedgehog signaling

Fig. 1

Relevance of SUV39H2 expression in human glioma. a The mRNA expression levels of SUV39H2 were assessed by RT-qPCR in 26 tumor tissues and their matched normal tissues (paired t test). b In the GSE4290 database, the mRNA expression levels of SUV39H2 were analyzed in glioblastoma and normal tissues (t test). c SUV39H2 was assessed in glioma tissues (n = 26) and matched normal tissues (n = 26) by IHC staining. A 10-point quantification scale (1–5, low; 6–10, high) was applied to indicate SUV39H2 staining indexes (χ2 test, p < 0.05). d A 10-point quantification scale (1–5, low; 6–10, high) was applied to indicate SUV39H2 staining indexes in different grades of glioma tissues (Kruskal–Wallis test). e Kaplan–Meier survival curves of patients based on SUV39H2 expression in the GSE43107 database (log-rank test). f, g The mRNA (f) and protein (g) expression levels of SUV39H2 in different glioma cell lines (t test). Data are shown as the mean ± SEM. (*p < 0.05, **p < 0.01, ***p < 0.001)

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