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Fig. 2 | Cancer Cell International

Fig. 2

From: Histone methyltransferase SUV39H2 regulates cell growth and chemosensitivity in glioma via regulation of hedgehog signaling

Fig. 2

SUV39H2 knockdown inhibits the tumorigenesis of glioma cells in vitro. a The expression of the indicated proteins assessed by WB in control (CTRL) and SUV39H2-knockdown (SUV39H2-sh) U251 or U87 cells. b Cell viability was assessed by the CCK-8 assay in CTRL and SUV39H2-sh U251 or U87 cells. c Representative images and cartograms of the colony formation assay in CTRL and SUV39H2-sh U251 or U87 cells. d Flow cytometry was performed to assess the effects of SUV39H2 on the cell cycle in CTRL and SUV39H2-sh U251 or U87 cells. e The expression of the indicated proteins assessed by WB in control (CTRL) and SUV39H2-knockdown (SUV39H2-sh) U251 or U87 cells. Data are shown as the mean ± SEM of at least three independent experiments. (*p < 0.05, **p < 0.01, ***p < 0.001, Student’s t-test)

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Cancer Cell International

ISSN: 1475-2867

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