Table 4 Treatment and follow-up of 12 cases with major discrepancies
Case ID | Diagnosis | Stage | Treatment | Pathologic response (if NACT) | Follow-up year (diagnosis) | Impact |
|---|---|---|---|---|---|---|
1 | IDC | pT1c N0 | Surgery Adjuvant chemotherapy Radiation | N/A | 4 (free of disease) | No hormonal therapy |
2 | IDC | ypT1a N0 | NACT surgery Adjuvant radiation Hormone therapy | Partial | 3 (free of disease) | Hormonal therapy |
3 | ILC | ypT3N3a | NACT surgery Adjuvant radiation | Partial | 3 (developed TN Chest wall recurrence) | No hormonal therapy |
4 | IDC | ypT1cN1a | NACT surgery Adjuvant radiation | Almost complete | 3 (free of disease) | No hormonal therapy |
5 | IDC | pT1cN0 | Surgery Adjuvant chemotherapy | N/A | 3 (free of disease) | No hormonal therapy |
6 | IDC | ypT1aN2a | NACT surgery Adjuvant radiation | Partial | 1 (progressive metastatic disease and lost to follow-up) | No hormonal therapy |
7 | IDC | cT2N3M1 | Palliative chemotherapy (un-resectable disease) | N/A | 1 (progressive disease and lost to follow-up) | No hormonal therapy |
8 | IDC | pT3N0 | Surgery Adjuvant chemotherapy radiation | N/A | 2 (progressive TN disease) | No hormonal therapy (ER, PR, and HER2 repeated at excision were negative) |
9 | IDC | cT2N0 | NACT (outside hospital) | N/A | N/A (lost to follow-up/ transferred care) | Â |
10 | IDC | cT2N1M1 | Chemotherapy radiation (bone met) |  | 3 (progressive ER+ disease) | Hormonal therapy (Primary breast carcinoma ER: 10%, PR: 0%) |
11 | IDC | ypT2N1 | NACT surgery Adjuvant radiation | Â | 3 (local recurrence TN progressive disease) | No hormonal therapy |
12 | IDC | ypT2N1mi | NACT surgery Adjuvant radiation | Â | 2 (metastasis progressive disease: ER, PR, HER2 unknown) | No hormonal therapy |