The predictive value of dynamic monitoring of peripheral blood lymphocyte to monocyte ratio in patients with extranodal NK/T cell lymphoma

Table 2 Univariate analysis of risk factors associated with OS and PFS

Variables	OS		PFS
Variables	HR (95% CI)	P value	HR (95% CI)	P value
Age (> 60 vs. ≤ 60)	1.80 (0.98–3.81)	0.065	1.04 (0.52–2.30)	0.205
Gender (male vs. female)	1.45 (1.07–1.92)	0.052	0.29 (0.13–0.86)	0.905
B symptoms (yes vs. no)	0.68 (0.24–1.63)	0.024	0.35 (0.12–1.98)	0.032
Lugano stage (I–II₂ vs. III–IV)	2.28 (1.28–4.14)	0.001	1.52 (0.65–3.58)	0.018
LDH (elevated vs. normal)	1.31 (1.04–1.67)	0.015	0.67 (0.33–1.42)	0.327
Local tumor invasiveness (yes vs. no)	0.46 (0.22–0.96)	0.024	0.32 (0.15–0.66)	0.037
Treatment (chemotherapy or radiotherapy vs. both)	0.67 (0.33–1.42)	0.004	0.35 (0.12–2.30)	0.041
Absolute lymphocyte count (≤ 1.5 × 10⁹/L vs. > 1.5 × 10⁹/L)	1.56 (0.72–3.40)	0.002	1.24 (0.62–2.08)	0.006
Absolute monocyte count (≤ 0.5 × 10⁹/L vs. > 0.5 × 10⁹/L)	0.53 (0.21–1.37)	0.102	0.45 (0.13–2.49)	0.361
LMR (≤ 2.7 vs. > 2.7)	4.21 (1.53–11.56)	0.000	2.78 (1.15–6.76)	0.034