Table 1 Relationships between CDK5RAP3 protein expressions in GNEC tissues and various clinicopathological characteristic
Variables | Total | C3 expression | |||
|---|---|---|---|---|---|
Low | High | X2 | P | ||
Gender | 0.221 | 0.638 | |||
Male | 43 | 20 | 23 | ||
Female | 8 | 3 | 5 | ||
Age (years) | 0.634 | 0.426 | |||
> 60 | 34 | 14 | 20 | ||
≤ 60 | 17 | 9 | 8 | ||
Tumor size (cm) | 3.804 | 0.051 | |||
> 5 | 35 | 19 | 16 | ||
≤ 5 | 16 | 4 | 12 | ||
Tumor location | 4.819 | 0.090 | |||
Lower 1/3 | 9 | 7 | 2 | ||
Middle 1/3 | 9 | 3 | 6 | ||
Upper 1/3 | 33 | 13 | 20 | ||
Histological type | 2.003 | 0.157 | |||
Large cell type | 32 | 12 | 20 | ||
Small cell type | 19 | 11 | 18 | ||
Depth of invasion | 22.203 | < 0.001 | |||
T1 | 2 | 2 | 0 | ||
T2 | 7 | 0 | 7 | ||
T3 | 29 | 9 | 20 | ||
T4 | 13 | 12 | 1 | ||
Lymph node metastasis | 4.104 | 0.043 | |||
N0 | 11 | 1 | 9 | ||
N1–3 | 40 | 21 | 19 | ||
Distant metastasis | 2.534 | 0.111 | |||
Negative | 49 | 21 | 28 | ||
Positive | 2 | 2 | 0 | ||
TNM stage | 5.368 | 0.021 | |||
I + II | 20 | 5 | 15 | ||
III + IV | 31 | 18 | 13 | ||