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Fig. 5 | Cancer Cell International

Fig. 5

From: PADI3 plays an antitumor role via the Hsp90/CKS1 pathway in colon cancer

Fig. 5

Function of PADI3 on CKS1 overexpression induced cell colony formation and proliferation in HCT116 cells. a GFP stable expressing HCT116 cells as the negative control, CKS1stable expressing HCT116 cells as the positive control, PADI3 overexpression plasmid was transfected into the CKS1 stable expressing HCT116 cells to study the function of PADI3 on CKS1 induced cell colony formation activity, 5 μM 17-AAG was used to treat CKS1stable expressing HCT116 cells to study the function of 17-AAG on CKS1 induced cell colony formation activity; b statistic analysis of colony formation results in a; c CCK8 was used to study the function of PADI3 and 17-AAG on CKS1 induced cell proliferation at 0 h, 12 h, 24 h and 48 h. *Indicates p < 0.05 for three independent experiments analyzed by Student’s t test

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