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Table 1 The demographics and clinical features of hepatocellular carcinoma patients in model cohort and validation cohort

From: Two predictive precision medicine tools for hepatocellular carcinoma

 

Model cohort

Validation cohort

P value

Patients (n)

348

203

 

Death [n (%)]

130 (37.4)

81 (39.9)

0.553

Survival time (month)

20.5 (11.9, 37.7)

51.3 (16.2, 57.3)

< 0.001

Age (year)

59.5 ± 13.4

51.1 ± 10.6

< 0.001

Male [n (%)]

236 (67.8)

174 (85.7)

< 0.001

Grade1 [n (%)]

53 (15.2)

NA

 

Grade2 [n (%)]

163 (46.8)

NA

 

Grade3 [n (%)]

115 (33.0)

NA

 

Grade4 [n (%)]

12 (3.4)

NA

 

AJCC PT1 [n (%)]

171 (49.1)

NA

 

AJCC PT2 [n (%)]

87 (25.0)

NA

 

AJCC PT3 [n (%)]

74 (21.3)

NA

 

AJCC PT4 [n (%)]

14 (4.0)

NA

 

AJCC PN0 [n (%)]

244 (70.1)

NA

 

AJCC PN1 [n (%)]

3 (0.9)

NA

 

AJCC PN2 [n (%)]

100 (28.7)

NA

 

AJCC PM0 [n (%)]

248 (71.3)

NA

 

AJCC PM1 [n (%)]

100 (28.7)

NA

 

AJCC stage1 [n (%)]

164 (47.1)

83 (40.9)

0.033

AJCC stage2 [n (%)]

79 (22.7)

71 (35.0)

 

AJCC stage3 [n (%)]

80 (23.0)

48 (23.6)

 

AJCC stage4 [n (%)]

4 (1.1)

0

 

Child–pugh1 [n (%)]

210 (60.3)

NA

 

Child pugh2 [n (%)]

20 (5.7)

NA

 

Child pugh3 [n (%)]

1 (0.3)

NA

 

Radiation treatment [n (%)]

4 (1.1)

NA

 

Pharmaceutical [n (%)]

15 (4.3)

NA

 

Ablation embolization [n (%)]

13 (3.7)

NA

 

Family history [n (%)]

106 (30.5)

NA

 
  1. The survival time was expressed as median (first quantile, third quantile). Continuous variables were compared by t-test or Mann–Whitney U test as appropriate. Categorical variables were compared by Chi-squared test or Fisher’s exact test as appropriate