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Table 1 The demographics and clinical features of hepatocellular carcinoma patients in model cohort and validation cohort

From: Two predictive precision medicine tools for hepatocellular carcinoma

 Model cohortValidation cohortP value
Patients (n)348203 
Death [n (%)]130 (37.4)81 (39.9)0.553
Survival time (month)20.5 (11.9, 37.7)51.3 (16.2, 57.3)< 0.001
Age (year)59.5 ± 13.451.1 ± 10.6< 0.001
Male [n (%)]236 (67.8)174 (85.7)< 0.001
Grade1 [n (%)]53 (15.2)NA 
Grade2 [n (%)]163 (46.8)NA 
Grade3 [n (%)]115 (33.0)NA 
Grade4 [n (%)]12 (3.4)NA 
AJCC PT1 [n (%)]171 (49.1)NA 
AJCC PT2 [n (%)]87 (25.0)NA 
AJCC PT3 [n (%)]74 (21.3)NA 
AJCC PT4 [n (%)]14 (4.0)NA 
AJCC PN0 [n (%)]244 (70.1)NA 
AJCC PN1 [n (%)]3 (0.9)NA 
AJCC PN2 [n (%)]100 (28.7)NA 
AJCC PM0 [n (%)]248 (71.3)NA 
AJCC PM1 [n (%)]100 (28.7)NA 
AJCC stage1 [n (%)]164 (47.1)83 (40.9)0.033
AJCC stage2 [n (%)]79 (22.7)71 (35.0) 
AJCC stage3 [n (%)]80 (23.0)48 (23.6) 
AJCC stage4 [n (%)]4 (1.1)0 
Child–pugh1 [n (%)]210 (60.3)NA 
Child pugh2 [n (%)]20 (5.7)NA 
Child pugh3 [n (%)]1 (0.3)NA 
Radiation treatment [n (%)]4 (1.1)NA 
Pharmaceutical [n (%)]15 (4.3)NA 
Ablation embolization [n (%)]13 (3.7)NA 
Family history [n (%)]106 (30.5)NA 
  1. The survival time was expressed as median (first quantile, third quantile). Continuous variables were compared by t-test or Mann–Whitney U test as appropriate. Categorical variables were compared by Chi-squared test or Fisher’s exact test as appropriate