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Table 2 The model information of prognostic mRNA biomarkers in univariate and multivariable Cox regression analyses

From: Two predictive precision medicine tools for hepatocellular carcinoma

 

Univariate analyses

Coefficient

Multivariate analyses

HR

95% CI

P-value

HR

95% CI

P-value

N4BP3 (high vs. low)

2.135

1.492–3.054

0.001

1.012

2.751

1.883–4.019

0.001

COL15A1 (high vs. low)

0. 38

0.378–0.765

0.001

− 0.652

0.521

0.358–0.760

0.001

ADRA2B (high vs. low)

0.471

0.330–0.671

0.001

− 0.537

0.585

0.399–0.856

0.006

NDST3 (high vs. low)

0.575

0.404–0.818

0.002

− 0.414

0.661

0.460–0.949

0.025

E2F8 (high vs. low)

2.033

1.425–2.898

0.001

0.635

1.888

1.295–2.752

0.001

MAPT (high vs. low)

1.875

1.315–2.672

0.001

0.462

1.587

1.101–2.288

0.013

PZP (high vs. low)

0.597

0.420–0.849

0.004

− 0.464

0.629

0.440–0.898

0.011

HOXD9 (high vs. low)

1.842

1.294–2.623

0.001

0.374

1.453

1.011–2.089

0.044

  1. The median values of mRNA expression were used as cutoff values to stratify mRNA expression values into high expression group (as value 1) and low expression group (as value 0)