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Table 1 Analysis of the relation between PFKFB3 and PFKFB4 expression and the overall survival rate in the panel of cancers

From: The influence of PFK-II overexpression on neuroblastoma patients’ survival may be dependent on the particular isoenzyme expressed, PFKFB3 or PFKFB4

Cancer typePatient numberSourceP value for PFKFB3P value for PFKFB4
Acute myeloid leukemia422GEO ID:GSE376420.7130.704
Adrenocortical carcinoma79TCGA ID:ND0.083a0.076a
B-cell lymphoma414GEO ID:GSE108460.069b0.528
Bladder urothelial carcinoma224GEO ID:GSE328940.5080.331
Bladder urothelial carcinoma408TCGA ID:BLCA0.5550.352
Breast159GEO ID:GSE14560.4050.110
Breast130GEO ID:GSE690310.5270.913
Breast invasive carcinoma1096TCGA ID:BRCA0.3580.858
Cervical squamous cell carcinoma292TCGA ID:CESC0.032a0.026a
Cholangiocarcinoma36TCGA ID:CHOL0.8590.402
Colon200GEO ID:GSE175380.041a0.775
Esophageal adenocarcinomas70GEO ID:GSE194170.8540.098b
Esophageal carcinoma183TCGA ID:ESCA0.8140.384
Ewing sarcoma85GEO ID:GSE631570.073a0.094a
Glioblastoma80GEO ID:GSE76961.0001.000
Glioblastoma377ND ID:ND0.5250.286
Glioblastoma504ND ID:ND0.9640.387
Glioma490GEO ID:GSE1084740.3781.2e−09a
Glioma273GEO ID:GSE160110.1291.4e−10a
Glioma50GEO ID:GSE433780.7300.028a
Glioma pediatric47GEO ID:GSE195780.092a0.625
Intrinsic glioma subtypes95GEO ID:GSE431070.069b0.660
Head neck squamous cell carcinoma520TCGA ID:HNSC0.6400.875
Kidney renal clear cell carcinoma533TCGA ID:KIRC0.4640.542
Kidney renal papillary cell carcinoma290TCGA ID:KIRP0.012a0.064a
Liver hepatocellular carcinoma371TCGA ID:LIHC0.058a6.6e−05a
Lung106GEO ID:GSE31410.8190.100a
Lung adenocarcinoma515TCGA ID:LUAD0.8140.961
Tumor lymphoma162GEO ID:GSE584450.3150.486
Tumor lymphoma470GEO ID:GSE313120.4310.555
Mantle cell lymphoma122GEO ID:GSE932910.030b0.070a
Medulloblastoma612GEO ID:GSE852170.5760.720
Melanoma214GEO ID:GSE659040.6330.048a
Metastatic melanoma44GEO ID:GSE192340.5580.394
Myeloma542GEO ID:GSE26580.078b0.514
Neuroblastoma476GEO ID:GSE455471.8e−04a6.2e−04b
Neuroblastoma498GEO ID:GSE625646.8e−04a1.6e−06b
Neuroblastoma stage IV27GEO ID:GSE799100.9390.325
Neuroblastoma primary283GEO ID:GSE850470.090a3.3e−03b
Neuroblastoma247ND ID:ND0.2726.1e−03b
Neuroblastoma88GEO ID:GSE164760.3980.078b
Ovarian75GEO ID:GSE638853.9e−03b0.941
Ovarian adenocarcinoma107GEO ID:GSE261930.3710.302
Pancreatic subtypes96ND ID:ND0.070a0.058a
Pancreatic adenocarcinoma146TCGA ID:PAAD0.016b0.928
Pancreatic ductal adenocarcinoma102GEO ID:GSE215010.6150.598
Skin cutaneous melanoma468TCGA ID:SKCM0.1920.493
Stomach adenocarcinoma415TCGA ID:STAD0.2180.738
Thymoma120TCGA ID:THYM0.9520.113
  1. Bold italic indicates the p value below 0.05
  2. italic indicates the p value between 0.05 and 0.1
  3. ND no data
  4. aHigh is worse
  5. bHigh is better