Table 1 Analysis of the relation between PFKFB3 and PFKFB4 expression and the overall survival rate in the panel of cancers

Acute myeloid leukemia

422

GEO ID:GSE37642

0.713

0.704

Adrenocortical carcinoma

79

TCGA ID:ND

0.083^a

0.076^a

B-cell lymphoma

414

GEO ID:GSE10846

0.069^b

0.528

Bladder urothelial carcinoma

224

GEO ID:GSE32894

0.508

0.331

Bladder urothelial carcinoma

408

TCGA ID:BLCA

0.555

0.352

Breast

159

GEO ID:GSE1456

0.405

0.110

Breast

130

GEO ID:GSE69031

0.527

0.913

Breast invasive carcinoma

1096

TCGA ID:BRCA

0.358

0.858

Cervical squamous cell carcinoma

292

TCGA ID:CESC

0.032^a

0.026^a

Cholangiocarcinoma

36

TCGA ID:CHOL

0.859

0.402

Colon

200

GEO ID:GSE17538

0.041^a

0.775

Esophageal adenocarcinomas

70

GEO ID:GSE19417

0.854

0.098^b

Esophageal carcinoma

183

TCGA ID:ESCA

0.814

0.384

Ewing sarcoma

85

GEO ID:GSE63157

0.073^a

0.094^a

Glioblastoma

80

GEO ID:GSE7696

1.000

1.000

Glioblastoma

377

ND ID:ND

0.525

0.286

Glioblastoma

504

ND ID:ND

0.964

0.387

Glioma

490

GEO ID:GSE108474

0.378

1.2e−09^a

Glioma

273

GEO ID:GSE16011

0.129

1.4e−10^a

Glioma

50

GEO ID:GSE43378

0.730

0.028^a

Glioma pediatric

47

GEO ID:GSE19578

0.092^a

0.625

Intrinsic glioma subtypes

95

GEO ID:GSE43107

0.069^b

0.660

Head neck squamous cell carcinoma

520

TCGA ID:HNSC

0.640

0.875

Kidney renal clear cell carcinoma

533

TCGA ID:KIRC

0.464

0.542

Kidney renal papillary cell carcinoma

290

TCGA ID:KIRP

0.012^a

0.064^a

Liver hepatocellular carcinoma

371

TCGA ID:LIHC

0.058^a

6.6e−05^a

Lung

106

GEO ID:GSE3141

0.819

0.100^a

Lung adenocarcinoma

515

TCGA ID:LUAD

0.814

0.961

Tumor lymphoma

162

GEO ID:GSE58445

0.315

0.486

Tumor lymphoma

470

GEO ID:GSE31312

0.431

0.555

Mantle cell lymphoma

122

GEO ID:GSE93291

0.030^b

0.070^a

Medulloblastoma

612

GEO ID:GSE85217

0.576

0.720

Melanoma

214

GEO ID:GSE65904

0.633

0.048^a

Metastatic melanoma

44

GEO ID:GSE19234

0.558

0.394

Myeloma

542

GEO ID:GSE2658

0.078^b

0.514

Neuroblastoma

476

GEO ID:GSE45547

1.8e−04^a

6.2e−04^b

Neuroblastoma

498

GEO ID:GSE62564

6.8e−04^a

1.6e−06^b

Neuroblastoma stage IV

27

GEO ID:GSE79910

0.939

0.325

Neuroblastoma primary

283

GEO ID:GSE85047

0.090^a

3.3e−03^b

Neuroblastoma

247

ND ID:ND

0.272

6.1e−03^b

Neuroblastoma

88

GEO ID:GSE16476

0.398

0.078^b

Ovarian

75

GEO ID:GSE63885

3.9e−03^b

0.941

Ovarian adenocarcinoma

107

GEO ID:GSE26193

0.371

0.302

Pancreatic subtypes

96

ND ID:ND

0.070^a

0.058^a

Pancreatic adenocarcinoma

146

TCGA ID:PAAD

0.016^b

0.928

Pancreatic ductal adenocarcinoma

102

GEO ID:GSE21501

0.615

0.598

Skin cutaneous melanoma

468

TCGA ID:SKCM

0.192

0.493

Stomach adenocarcinoma

415

TCGA ID:STAD

0.218

0.738

Thymoma

120

TCGA ID:THYM

0.952

0.113