Table 1 Correlation between expression of SNAI2, E-cadherin, N-cadherin and clinicopathological characteristics of GIST patients
Item | n | SNAI2 (+) | χ2 | P value | E-cad (+) | χ2 | P value | N-cad (+) | χ2 | P value | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
n | % | n | % | n | % | ||||||||
Gender | |||||||||||||
 Male | 48 | 28 | 58.3 |  |  | 21 | 43.8 |  |  | 39 | 81.3 |  |  |
 Female | 30 | 14 | 46.7 | 1.01 | 0.32 | 7 | 23.3 | 3.34 | 0.07 | 20 | 66.7 | 2.13 | 0.14 |
Age | |||||||||||||
 < 50 years | 40 | 24 | 60.0 |  |  | 13 | 32.5 |  |  | 29 | 72.5 |  |  |
 > 50 years | 38 | 18 | 47.4 | 1.25 | 0.26 | 15 | 39.5 | 0.41 | 0.52 | 30 | 78.9 | 0.44 | 0.51 |
Position | |||||||||||||
 Stomach | 47 | 24 | 51.1 |  |  | 15 | 31.9 |  |  | 35 | 74.5 |  |  |
 Intestine | 26 | 15 | 57.7 |  |  | 10 | 38.5 |  |  | 21 | 80.8 |  |  |
 Colorectum | 5 | 3 | 60 | 0.38 | 0.83 | 3 | 60 | 1.66 | 0.44 | 3 | 60 | 1.07 | 0.59 |
Risk category | |||||||||||||
 Very low | 5 | 2 | 40 |  |  | 2 | 40 |  |  | 4 | 80.0 |  |  |
 Low | 20 | 11 | 55 |  |  | 9 | 45 |  |  | 16 | 80.0 |  |  |
 Mid | 22 | 9 | 40.9 |  |  | 9 | 40.9 |  |  | 14 | 63.6 |  |  |
 High | 31 | 20 | 64.5 | 3.30 | 0.348 | 8 | 25.8 | 2.37 | 0.50 | 25 | 80.6 | 2.4 | 0.49 |
Local invasion | |||||||||||||
 Yes | 41 | 25 | 61 |  |  | 16 | 39.0 |  |  | 29 | 70.7 |  |  |
 No | 37 | 17 | 45.9 | 1.77 | 0.18 | 12 | 32.4 | 0.37 | 0.54 | 30 | 81.1 | 1.13 | 0.29 |
Distant metastasis | |||||||||||||
 Yes | 24 | 18 | 75 |  |  | 4 | 16.7 |  |  | 20 | 83.3 |  |  |
 No | 54 | 24 | 4.4 | 6.24 | 0.01 | 24 | 44.4 | 5.57 | 0.02 | 39 | 72.2 | 1.11 | 0.29 |