Fig. 4

The function of TRIM11 was abolished by the AKT inhibitor LY294002 in chordoma cells. a The AKT inhibited the proliferation rate of oeTRIM11 transfected cells; *p < 0.05 vs oeNC, ***p < 0.001 vs oeNC; ^#p < 0.05 vs oeTRIM11, ^###p < 0.001 vs oeTRIM11. b The cell apoptosis was upregulated by the AKT inhibitor LY294002 in oeTRIM11 transfected cells; ***p < 0.001 vs oeNC, ^###p < 0.001 vs oeTRIM11. c Western blot was used to examine the protein content of XIAP, cleaved caspase-3, p-AKT and AKT in cells as indicated; *p < 0.05 vs oeNC, **p < 0.01 vs oeNC, ***p < 0.001 vs oeNC; ^###p < 0.001 vs oeTRIM11