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Fig. 6 | Cancer Cell International

Fig. 6

From: RETRACTED ARTICLE: Silencing of TRIM11 suppresses the tumorigenicity of chordoma cells through improving the activity of PHLPP1/AKT

Fig. 6

Overexpression of PHLPP1 suppressed the function of TRIM11 in chordoma cells. a, b The relative mRNA and protein level of PHLPP1 were significantly upregulated in oePHLPP1 transfected cells. ***p < 0.001 vs oeNC. b Overexpression of PHLPP1 promoted the apoptosis of orTRIM11 transfected cells. *p < 0.05 vs oeNC, ***p < 0.001 vs oeNC; ###p < 0.001 vs oeTRIM11; !!!p < 0.001 vs oePHLPP1. d The phosphorylation of AKT was inhibited in oePHLPP1 transfected cells, ***p < 0.001 vs oeNC; ###p < 0.001 vs oeTRIM11

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