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Fig. 5 | Cancer Cell International

Fig. 5

From: Low BCL9 expression inhibited ovarian epithelial malignant tumor progression by decreasing proliferation, migration, and increasing apoptosis to cancer cells

Fig. 5

Inhibition of BCL9 may inhibit the invasion and migration of ovarian cancer cells by inhibiting MMP2 and MMP9. a The results of the scratch test showed that the migration distance of ovarian cancer cells in the low BCL9 expression group after 24 h was significantly less than in the control group. b The transwell test results showed that the cell migration ability of ovarian cancer cells with low BCL9 expression decreased within 24 h compared with the control group, and the cell invasion ability decreased within 48 h. c, d After inhibiting BCL9 expression, the expression of MMP2 and MMP9 significantly decreased in ES-2 cells (*P < 0.05, **P < 0.01), but BCL9 expression did not affect β-catenin expression

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Cancer Cell International

ISSN: 1475-2867

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