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Fig. 6 | Cancer Cell International

Fig. 6

From: The lncRNA DLX6-AS1 promoted cell proliferation, invasion, migration and epithelial-to-mesenchymal transition in bladder cancer via modulating Wnt/β-catenin signaling pathway

Fig. 6

Knockdown of DLX6-AS1 inhibited in vivo tumor growth. a Analysis of tumor growth in nude mice inoculated with T24 cells (transfected control shRNA or DLX6-AS1 shRNA). b Analysis of tumor weight of the dissected tumor tissues from control shRNA and DLX6-AS1 shRNA groups. c Analysis of DLX6-AS1 expression by qRT-PCR in tumor tissues from control shRNA and DLX6-AS1 shRNA groups. d, e Analysis of E-cadherin vimentin, and N-cadherin mRNA and protein expression by qRT-PCR and western blot, respectively, in tumor tissues from control shRNA and DLX6-AS1 shRNA group. f, g Analysis of β-catenin, GSK-3β, c-myc and cyclin D1 mRNA and protein expression by qRT-PCR and western blot, respectively, in tumor tissues from control shRNA and DLX6-AS1 shRNA group. N = 5; significant differences between different groups were shown as *P < 0.05, **P < 0.01 and ***P < 0.001

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