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Table 5 Genotype and allele frequencies for the MTHFR C677T polymorphism in mild, moderate and severe EPL cases

From: MTHFR C677T genetic polymorphism in combination with serum vitamin B2, B12 and aberrant DNA methylation of P16 and P53 genes in esophageal squamous cell carcinoma and esophageal precancerous lesions: a case–control study

MTHFR C677T
genotype frequencies
Mild EPL
n (%)
Moderate EPLSevere EPL
n (%)OR (95% CI)p valuen (%)OR (95% CI)p value
CC49 (50.5)27 (37.0)1.00 9 (30.0)1.00 
CT35 (36.1)34 (46.6)1.76 (0.91–3.43)0.0911 (36.7)1.71 (0.64–4.57)0.28
TT13 (13.4)12 (16.4)1.68 (0.67–4.18)0.2710 (33.3)4.19 (1.41–12.44)0.01
C133 (68.6)88 (60.3)1.00 29 (48.4)1.00 
T61 (31.5)58 (39.7)1.44 (0.92–2.25)0.1131 (51.7)2.33 (1.29–4.21)0.01