Fig. 6

MiR-135a-5p inhibition exacerbated tumor cell progression through activating KLF8 in vitro. a Relative expression of KLF8 protein in SCC9 cells was tested by western blot. b The viability of SCC9 cells was assessed by MTT assay. c, d The migration and invasion of SCC9 cells was measured using wound healing assay and transwell assay, respectively. e Relative expression of MMP-2 and MMP-9 protein in SCC9 cells was examined using western blot. **p < 0.01, ***p < 0.001, versus to NC inhibitor; ^&p < 0.05, ^&&p < 0.01, ^&&&p < 0.001, versus to miR-135a-5p inhibitor + si-NC