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Fig. 3 | Cancer Cell International

Fig. 3

From: MicroRNA-140-5p inhibits salivary adenoid cystic carcinoma progression and metastasis via targeting survivin

Fig. 3

MiR-140-5p targeted survivin 3′UTR and suppressed survivin expression. a Putative binding sites between miR-140-5p and survivin 3′UTR as predicted using online StarBase 2.0 tool. b, c Relative luciferase activity of different reporter constructs in SACC-83 and SACC-LM cells after being transfected with mimics NC or miR-140-5p mimics. d, e qRT-PCR and western blot assays respectively determined survivin mRNA and protein expression levels in SACC-83 and SACC-LM cells after being transfected with mimics NC or miR-140-5p mimics. f, g qRT-PCR and western blot assays respectively determined survivin mRNA and protein expression levels in SACC-83 and SACC-LM cells after being transfected with inhibitors NC or miR-140-5p inhibitors. N = 3. Significant difference between treatment groups were indicated as *P < 0.05 and **P < 0.01

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