Fig. 4From: PAX8 expression in high-grade serous ovarian cancer positively regulates attachment to ECM via Integrin β3Integrin β3 overexpression is able to reverse the effects of PAX8 silencing. The cell migrated area and the adhesion ability to Fibronectin or Collagen I of KURAMOCHI and PEA1 cells was analyzed 48 h after transient transfection with scramble siCTR, siPAX8 or siPAX8 + ITGB3 expression vector. In all the experiments, the values are means ± SD of three independent experiments normalized with respect to the cells transfected with the scramble siRNA. p-value was calculated by t-test p ≤ 0.1Back to article page