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Fig. 4 | Cancer Cell International

Fig. 4

From: PAX8 expression in high-grade serous ovarian cancer positively regulates attachment to ECM via Integrin β3

Fig. 4

Integrin β3 overexpression is able to reverse the effects of PAX8 silencing. The cell migrated area and the adhesion ability to Fibronectin or Collagen I of KURAMOCHI and PEA1 cells was analyzed 48 h after transient transfection with scramble siCTR, siPAX8 or siPAX8 + ITGB3 expression vector. In all the experiments, the values are means ± SD of three independent experiments normalized with respect to the cells transfected with the scramble siRNA. p-value was calculated by t-test p ≤ 0.1

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