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Table 2 Univariate and multivariate Cox regression analyses in TCGA cohort

From: A panel of Transcription factors identified by data mining can predict the prognosis of head and neck squamous cell carcinoma

VariablesPatientsUnivariable analysisMultivariate analysis
HR (95% CI)P valueHR (95% CI)P value
Gender (male/female)366/1320.329–1.9260.612  
Age (60 vs. > 60)217/2810.978–1.6160.069  
Alcohol (no/yes)157/3300.731–1.2960.893  
HPV (no/yes)64/190.622–2.4810.416  
Lymph node neck dissection (yes/no)405/900.971–1.8880.074  
Histologic grade (G1/G2/G3/G4)61/297/119/20.893–1.3540.370  
TNM stage (I/II/III/IV)25/70/78/2571.186–1.701< 0.0010.805–1.5410.541
Lympho-vascular invasion (no/yes)218/1191.208–2.3840.0020.588–1.4420.691
Perineural invasion present (no/yes)186/1631.557–3.116< 0.0011.162–2.8620.009
Extranodal extension (no/yes)290/1061.989–3.716< 0.0011.488–3.817< 0.001
Risk (low-risk/high-risk)357/1412.119–3.668< 0.0011.182–2.7500.006