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Fig. 6 | Cancer Cell International

Fig. 6

From: MicroRNA-1269 promotes cell proliferation via the AKT signaling pathway by targeting RASSF9 in human gastric cancer

Fig. 6

RASSF9 overexpression inhibits the proliferation of human GC cells. a RASSF9 overexpression promoted RASSF9 mRNA levels in AGS/MKN-45 cells. b MTT assay showed that RASSF9 overexpression decreased AGS/MKN-45 cell activity at 48 and 72 h. c Cell counting assay showed that RASSF9 overexpression inhibited AGS/MKN-45 cell growth. d The cell cycle was measured in AGS/MKN-45 cells at 48 h. e Apoptosis was examined in AGS/MKN-451 cells at 48 h. f RASSF9, p-AKT, AKT, Cyclin D1, CDK2, Bcl-2 and Bax expression levels were detected after transfection with the RASSF9 overexpression vector. Wilcoxon test, *p < 0.01, n = 3

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