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Table 1 A total of 76 deregulated genes were identified in 1839 primary tumor versus metastatic lymph node genes

From: Expression profile analysis identifies IER3 to predict overall survival and promote lymph node metastasis in tongue cancer

Gene symbollogFCP valueHallmark
MBL21.8363550.016409ALLOGRAFT_REJECTION
ITGAL1.096150.029208ALLOGRAFT_REJECTION
CD3G1.0849880.023672ALLOGRAFT_REJECTION
FLNA1.0030190.037726ALLOGRAFT_REJECTION
GLMN− 1.110450.044154ALLOGRAFT_REJECTION
VAV21.2224830.037575ANGIOGENESIS, APICAL_JUNCTION
ACTA1− 4.812430.007734APICAL_JUNCTION
EFHC1− 1.331060.001242BILE_ACID_METABOLISM
DIO2− 1.487140.003577BILE_ACID_METABOLISM
SMC6− 1.013780.036294E2F_TARGETS
ORC2− 1.021710.039099E2F_TARGETS
LUC7L3− 1.216090.002313E2F_TARGETS
MRE11A− 1.230030.045764E2F_TARGETS
ABCA3− 1.43870.009719ESTROGEN_RESPONSE_EARLY, ESTROGEN_RESPONSE_LATE
TTC39A− 1.909270.002779ESTROGEN_RESPONSE_EARLY
NPY1R2.0204640.03779ESTROGEN_RESPONSE_LATE, ESTROGEN_RESPONSE_EARLY
GAL1.4683470.023249ESTROGEN_RESPONSE_LATE
EGR31.1774850.036595ESTROGEN_RESPONSE_LATE, ESTROGEN_RESPONSE_EARLY, KRAS_SIGNALING_UP
CASC51.8976060.036429G2M_CHECKPOINT
CASP8AP2− 1.090860.016979G2M_CHECKPOINT
EZH2− 1.187210.018306G2M_CHECKPOINT, E2F_TARGETS
MNAT1− 1.271080.027402G2M_CHECKPOINT
SMC2− 1.339820.04864G2M_CHECKPOINT
SERPINE11.7330880.021088HYPOXIA
FOS1.5435770.005153HYPOXIA
IER31.3875160.015602HYPOXIA, APOPTOSIS
ANGPTL41.2616860.018984HYPOXIA, KRAS_SIGNALING_UP, ADIPOGENESIS
SLC2A5− 2.147470.047968HYPOXIA
SOCS31.728430.019538IL6_JAK_STAT3_SIGNALING
INHBE− 1.170540.031406IL6_JAK_STAT4_SIGNALING
ZNF6392.5111510.001222KRAS_SIGNALING_UP
RBP42.2296250.033045KRAS_SIGNALING_UP
CD371.5474970.019287KRAS_SIGNALING_UP
GFPT21.0315060.042835KRAS_SIGNALING_UP
SLMO2− 1.000920.02985KRAS_SIGNALING_UP
CFH− 1.66920.040962KRAS_SIGNALING_UP
SLPI− 1.674310.014661KRAS_SIGNALING_UP
BTC− 2.141050.00012KRAS_SIGNALING_UP
TMEM158− 2.441140.000586KRAS_SIGNALING_UP
SVIL− 1.153720.004237MYOGENESIS
IFRD1− 1.297770.000871MYOGENESIS
AGL− 1.345630.006822MYOGENESIS
FABP3− 1.391620.018123MYOGENESIS
CKMT2− 1.433260.0434MYOGENESIS
MYH8− 1.485480.015832MYOGENESIS
DMD− 1.537310.006311MYOGENESIS, G2M_CHECKPOINT
MYOZ1− 1.740480.041979MYOGENESIS
CHRNA1− 1.80810.017455MYOGENESIS
HRC− 2.021060.038865MYOGENESIS
FHL1− 2.036880.035865MYOGENESIS
SLN− 2.114690.041452MYOGENESIS
ACTC1− 2.909680.011697MYOGENESIS
DES− 3.033880.031095MYOGENESIS
MYBPH− 3.217110.003079MYOGENESIS
TNNT1− 3.345170.024009MYOGENESIS
MYH2− 3.35030.042848MYOGENESIS
MB− 3.350380.010556MYOGENESIS
TCAP− 3.388710.029364MYOGENESIS
MYLPF− 3.502660.020669MYOGENESIS
TNNC2− 3.521480.020435MYOGENESIS
MYL2− 3.599380.011658MYOGENESIS
ACTN2− 4.314630.01354MYOGENESIS
TNNI2− 4.429650.011318MYOGENESIS
MYL1− 4.548430.006995MYOGENESIS
CKM− 4.718580.011289MYOGENESIS
TNNI1− 4.776360.0062MYOGENESIS
TNNC1− 5.648250.007417MYOGENESIS
CSRP3− 5.773250.012999MYOGENESIS
PPP2R1B1.1717970.042423PI3K_AKT_MTOR_SIGNALING
FGF17− 1.340210.032683PI3K_AKT_MTOR_SIGNALING
IL4− 1.520420.040415PI5K_AKT_MTOR_SIGNALING, IL6_JAK_STAT3_SIGNALING
ADCY2− 1.914340.025949PI6K_AKT_MTOR_SIGNALING
SH3GL21.5084130.042024PROTEIN_SECRETION
OCRL− 1.096720.008807PROTEIN_SECRETION
JUNB1.0476070.019591REACTIVE_OXIGEN_SPECIES_PATHWAY
GCLM− 1.711760.003821REACTIVE_OXIGEN_SPECIES_PATHWAY, BILE_ACID_METABOLISM