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Fig. 5 | Cancer Cell International

Fig. 5

From: The long noncoding RNA PCGEM1 promotes cell proliferation, migration and invasion via targeting the miR-182/FBXW11 axis in cervical cancer

Fig. 5

PCGEM1 exerts oncogenic effects through miR-182. a The proliferation of HeLa cells transfected with miR-NC or miR-182 mimics was assessed by CCK-8 assay. b Transwell assay was performed in HeLa cells transfected with miR-NC or miR-182 mimics. c The proliferation of SiHa cells transfected with miR-NC or miR-182 inhibitor was assessed by CCK-8 assay. d Transwell assay was performed in SiHa cells transfected with miR-NC or miR-182 inhibitor. e The miR-182 mimics were transfected into PCGEM1 overexpressing SiHa cells, and the miR-182 expression was examined by qRT-PCR. f The miR-182 inhibitors were transfected into PCGEM1 silencing HeLa cells, and the miR-182 expression was examined by qRT-PCR. g miR-182 abolished the promotion of cell proliferation mediated by PCGEM1 overexpression in SiHa cells. h miR-182 inhibitors abolished the suppression of cell proliferation mediated by PCGEM1 siRNAs in HeLa cells. i miR-182 abolished the promotion of cell migration and invasion mediated by PCGEM1 overexpression in SiHa cells. j miR-182 inhibitors abolished the suppression of cell migration and invasion mediated by PCGEM1 siRNAs in HeLa cells. *p < 0.05, **p < 0.01

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