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Fig. 8 | Cancer Cell International

Fig. 8

From: The long noncoding RNA PCGEM1 promotes cell proliferation, migration and invasion via targeting the miR-182/FBXW11 axis in cervical cancer

Fig. 8

PCGEM1 activates NF-κB and β-catenin/TCF signaling pathways. a The dual luciferase method was used to analyze the activation of the NF-κB pathway in SiHa cells cotransfected with PCGEM1 and FBXW11 siRNAs. b The dual luciferase method was used to analyze the activation of the β-catenin/TCF signaling pathway in SiHa cells cotransfected with PCGEM1 and FBXW11 siRNAs, and a mutant TCF transcription factor (FOP) was used as a functional control. c The downstream gene of NF-κB and β-catenin/TCF signaling pathway was examined by qRT-PCR in in SiHa cells cotransfected with PCGEM1 and FBXW11 siRNAs. *p < 0.05, **p < 0.01

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