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Fig. 1 | Cancer Cell International

Fig. 1

From: Highly versatile cancer photoimmunotherapy using photosensitizer-conjugated avidin and biotin-conjugated targeting antibodies

Fig. 1

Schematic representations of AvIR-mediated PIT. Due to the cellular targeting by BioAb(s) specific to the tumor cells and/or tumor-supporting cells, AvIR can exert the phototoxicity only on the targeted cells upon NIR irradiation, without any damage to normal tissues. As long as cell type-specific BioAbs are available, potential therapeutic target cells of AvIR-PIT are virtually unlimited, allowing the highly integrated tumor control

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