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Fig. 5 | Cancer Cell International

Fig. 5

From: SWAP-70 promotes glioblastoma cellular migration and invasion by regulating the expression of CD44s

Fig. 5

CD44s overexpression partially reverses the inhibitory effect of downregulated SWAP-70 on glioblastoma cellular migration and invasion. a Transient transfection of the CD44s-overexpression plasmid in U251 cells with stable SWAP-70 downregulation. Transfection efficiency and protein expression of SWAP-70 and CD44s were assessed by Western blotting. b Statistical analysis of SWAP-70 and CD44s protein levels. c Effect of CD44s overexpression on the migratory ability of glioblastoma cells after downregulating SWAP-70 determined with the in vitro scratch assay. d Effect of CD44s overexpression on the invasive ability of glioblastoma cells after downregulating SWAP-70 analyzed with the transwell invasion assay. e Statistical analysis of the numbers of migrating and invading cells. All data are presented as the mean ± SEM (n = 3 per group; *P < 0.05)

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