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Table 3 Multivariate analysis of factors associated with overall survival and progression-free survival in LUAD patients

From: High CTHRC1 expression may be closely associated with angiogenesis and indicates poor prognosis in lung adenocarcinoma patients

Variables

OS

PFS

Hazard ratio

95% CI

P-value

Hazard ratio

95% CI

P-value

Gender

1.074

0.703–1.643

0.740

1.204

0.790–1.834

0.389

Age

3.223

1.917–5.418

< 0.001

2.097

1.344–3.273

0.001

Smoking

0.934

0.563–1.588

0.833

0.892

0.548–1.451

0.644

Tumor differentiation

0.946

0.563–1.588

0.833

1.318

0.802–2.164

0.276

Clinical stage

2.996

2.135–4.204

< 0.001

3.267

2.302–4.638

< 0.001

T classification

0.805

0.673–1.016

0.067

0.730

0.576–0.925

0.009

N classification

0.911

0.665–1.250

0.565

0.796

0.576–1.100

0.167

M classification

1.433

0.628–3.269

0.393

1.163

0.504–2.686

0.732

CTHRC1 expression

1.097

1.029–1.170

0.004

1.133

1.061–1.211

< 0.001

VEGF expression

0.987

0.927–1.051

0.680

1.033

0.970–1.100

0.313

MVD count

1.015

0.999–1.030

0.060

1.005

0.990–1.020

0.507

  1. CI confidence interval; statistical significance (P < 0.05) is shown in italic
  2. LUAD lung adenocarcinoma, OS overall survival, PFS progression-free survival, CTHRC1 collagen triple helix repeat containing 1, VEGF vascular endothelial growth factor, MVD microvessel density, TNM tumor-node-metastasis, CI confidence interval
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Cancer Cell International

ISSN: 1475-2867

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