Cancer Cell International

Table 5 Multivariate analysis of the predictive model with clinicopathologic characteristics in LUAD patients

From: High CTHRC1 expression may be closely associated with angiogenesis and indicates poor prognosis in lung adenocarcinoma patients

Variables	OS			PFS
Variables	Hazard ratio	95% CI	P-value	Hazard ratio	95% CI	P-value
Gender	0.880	0.571–1.357	0.564	1.088	0.713–1.662	0.695
Age	1.062	1.042–1.084	< 0.001	1.029	1.010–1.049	0.003
Smoking	1.071	0.655–1.752	0.784	0.878	0.541–1.427	0.601
Tumor differentiation	0.942	0.557–1.593	0.823	1.411	0.869–2.289	0.164
Clinical stage	2.792	1.990–3.918	< 0.001	3.165	2.236–4.480	< 0.001
T classification	0.840	0.664–1.063	0.146	0.727	0.575–0.920	0.008
N Classification	0.935	0.678–1.288	0.680	0.766	0.554–1.059	0.107
M Classification	1.633	0.729–3.661	0.233	1.318	0.869–2.289	0.517
The predictive model	1.795	1.291–2.496	0.001	2.301	1.671–3.168	< 0.001

CI confidence interval; statistical significance (P < 0.05) is shown in italic
LUAD lung adenocarcinoma, OS overall survival, PFS progression-free survival, TNM tumor-node-metastasis, CI Confidence interval

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