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Fig. 5 | Cancer Cell International

Fig. 5

From: Exosomal lncRNA HNF1A-AS1 affects cisplatin resistance in cervical cancer cells through regulating microRNA-34b/TUFT1 axis

Fig. 5

Exosomes shuttled HNF1A-AS1 down-regulates miR-34b and upregulates TUFT1 expression to promote the proliferation, drug resistance, and inhibit apoptosis of cervical cancer cells. a MTT assay was used to detect IC50 of DDP-treated cells in each group; b proliferation of DDP-treated cells using EdU assay. c Flow cytometry was used to detect apoptosis of DDP-treated cells. d RT-qPCR was used to detect the expression of miR-34b and TUFTI after overexpression of HNF1A-AS1-exo. *P < 0.05 vs. the NC-exo group. Measurement data were depicted as mean ± standard deviation, comparisons between groups were conducted by non-paired t test. The experiment was repeated three times

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