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Fig. 2 | Cancer Cell International

Fig. 2

From: S-15 in combination of Akt inhibitor promotes the expansion of CD45RA−CCR7+ tumor infiltrating lymphocytes with high cytotoxic potential and downregulating PD-1+Tim-3+ cells as well as regulatory T cells

Fig. 2

Frequencies of CD45RA−CCR7+ on CD8+ T cells in IL-2, IL-2/S-15, IL-2/Akti and IL-2/S-15/Akti-expanded Tils. a The dynamic percentages of Tcm within CD8+ T cells during the 25-day initial culture period were shown. Data represent the mean ± SEM of six independent experiments. b Representative dot plots with percentages of CD45RA−CCR7+ among the CD8+ T cell population in different groups at day 25 are shown. c Summary data about the percentages of CD45RA−CCR7+ within the CD8+ T cell population at day 25 which is from panel a are presented. Statistical significance was analyzed by repeated measures ANOVA

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Cancer Cell International

ISSN: 1475-2867

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