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Fig. 2 | Cancer Cell International

Fig. 2

From: LncRNA HCG11 promotes proliferation and migration in gastric cancer via targeting miR-1276/CTNNB1 and activating Wnt signaling pathway

Fig. 2

HCG11 accelerated the proliferation and migration in GC cells by activating Wnt signaling pathway. a Western blot was applied to measure key proteins of several signaling pathways. b, c Cell proliferation ability was decreased by knockdown of HCG11, examined by CCK8 and colony formation assay, which could be recovered by LiCl. d The rate of apoptosis was increased by sh-HCG11#1, which could be regained by LiCl. e The capacity of migration was impaired by sh-HCG11#1, which could be counteracted by LiCl. f TOP/FOP flash luciferase reporter assay was conducted to test the activity of signaling pathway. *P < 0.05, **P < 0.01

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