Fig. 1

HAND2-AS1 is poorly expressed in cervical cancer and cells. a The heat map of some differentially expressed genes in the cervical cancer expression dataset GSE63678. The abscissa indicates the sample type and the ordinate indicates the gene expression level. The left dendrogram indicates the sample expression cluster, and the upper right histogram indicates color grade. b The expression of HAND2-AS1 in dataset GSE63678. The abscissa indicates the sample type, and the ordinate indicates the gene expression; the upper right indicates p value. c The expression of HAND2-AS1 in 68 cases of cervical cancer and adjacent tissues determined by RT-qPCR (N = 68), *p < 0.05 vs. the adjacent tissues. d The expression of HAND2-AS1 in human cervical cancer cell lines, *p < 0.05 vs. HUCEC cell line. All measurements were expressed by mean ± standard deviation. Paired t-test was used for comparison between cervical cancer tissues and adjacent tissues. The expression of each cell line was compared with one-way ANOVA, followed by Tukey’s post hoc test. The experiment was repeated three times. HAND2-AS1 HAND2 antisense RNA 1, RT-qPCR reverse transcription quantitative polymerase chain reaction, ANOVA analysis of variance, HUCEC human cervical epithelial cell