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Fig. 7 | Cancer Cell International

Fig. 7

From: Silencing lncRNA ZFAS1 or elevated microRNA-135a represses proliferation, migration, invasion and resistance to apoptosis of osteosarcoma cells

Fig. 7

Declined ZFAS1 or elevated miR-135a represses APEX1 in MG63 cells. A mRNA expression of APEX1 in each group of MG63 cells detected by RT-qPCR. B APEX1 protein band and expression in each group of MG63 cells. C The binding sites of miR-135a and APEX1 predicted by bioinformatics website. D The regulatory relationship between miR-135a and APEX1 verified by dual luciferase reporter gene assay. The data in the figure were all measurement data, in the form of mean ± standard deviation; a vs the sh-NC group, P < 0.05; b vs the mimic-NC group, P < 0.05; c vs the sh-ZFAS1 + inhibitor NC group, P < 0.05

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