Fig. 2

miR-98-5p targets CDKN1A to inhibit CDKN1A expression. a The expression of related miRs in the CAF-derived exosomes as detected by RT-qPCR. b The binding sites between CDKN1A and miR-98-5p predicted by the TargetScan website. c The binding of miR-98-5p to CDKN1A as verified by dual luciferase reporter assay. d The expression of CDKN1A in OC cells after treatment of miR-98-5p mimic as detected by RT-qPCR. e The expression of CDKN1A in OC cells after treatment of miR-98-5p mimic as detected by Western blot analysis. f Statistical analysis for e. g Pearson’s correlation analysis of the correlation between the expression of miR-98-5p and CDKN1A in OC cells. *p < 0.05 vs. has-miR-98-5p or the treatment of mimic-NC. These data were measurement data, expressed as mean ± standard deviation. Data between two groups were compared using unpaired t-test. Data among multiple groups were compared using one-way analysis of variance and further analyzed with Tukey’s post hoc test. The correlation between two indices was analyzed using Pearson’s correlation analysis. The experiment was repeated three times