TY - JOUR AU - Zhang, Chengjuan AU - Zhang, Junxia AU - Wu, Qiong AU - Xu, Benling AU - Jin, Guoguo AU - Qiao, Yan AU - Zhao, Simin AU - Yang, Yang AU - Shang, Jinwen AU - Li, Xiaofang AU - Liu, Kangdong PY - 2019 DA - 2019/12/19 TI - Sulforaphene induces apoptosis and inhibits the invasion of esophageal cancer cells through MSK2/CREB/Bcl-2 and cadherin pathway in vivo and in vitro JO - Cancer Cell International SP - 342 VL - 19 IS - 1 AB - As a novel type of isothiocyanate derived from radish seeds from cruciferous vegetables, sulforaphene (SFE, 4-methylsufinyl-3-butenyl isothiocyanate) has various important biological effects, such as anti-oxidative and anti-bacterial effects. Recently, sulforaphene has attracted increasing attention for its anti-tumor effects and its ability to suppress the development of multiple tumors through different regulatory mechanisms. However, it has not yet been widely investigated for the treatment of esophageal cancer. SN - 1475-2867 UR - https://doi.org/10.1186/s12935-019-1061-1 DO - 10.1186/s12935-019-1061-1 ID - Zhang2019 ER -