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Fig. 3 | Cancer Cell International

Fig. 3

From: Sulforaphene induces apoptosis and inhibits the invasion of esophageal cancer cells through MSK2/CREB/Bcl-2 and cadherin pathway in vivo and in vitro

Fig. 3

Differentially expressed proteins and phosphorylated proteins induced by sulforaphene treatment. a The flow chart of the experiment. Global protein expression and phosphorylation levels in the control and sulforaphene treatment groups were detected by mass spectrometry. b Significantly upregulated and downregulated proteins upon sulforaphene treatment were identified through mass spectrometry assays. c The number of significantly upregulated and downregulated phosphorylated protein sites upon sulforaphene treatment. d The number of significantly upregulated and downregulated phosphorylated proteins upon sulforaphene treatment. e Volcano plots of differentially expressed proteins. f The cellular distribution of significantly upregulated proteins. g The cellular distribution of significantly downregulated proteins. h GO analysis heat map of differentially expressed proteins

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