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Fig. 2 | Cancer Cell International

Fig. 2

From: TGF-β1 stimulates epithelial–mesenchymal transition and cancer-associated myoepithelial cell during the progression from in situ to invasive breast cancer

Fig. 2

Expression of EMT markers in adjacent normal breast tissue, DCIS and IDC. a1 Preserved membrane staining for E-cadherin in healthy breast tissue and DCIS (b1); c1 loss of E-cadherin in IDC. a2 Negative expression of N-cadherin in adjacent normal breast tissue and DCIS (b2); c2 increased membrane N-cadherin expression is evident in IDC. a3 Negative expression of snail in healthy breast tissue and DCIS (b3); c3 increased cytoplasmic expression of Snail is evident in IDC. a4 Negative expression of Twist in healthy breast tissue and DCIS (b4); c4 increased cytoplasmic expression of Twist is evident in IDC. a5 Negative expression of Vimentin in healthy breast tissue and DCIS (b5); c5 increased cytoplasmic expression of Vimentin is evident in IDC. a6 Negative expression of Zeb1 in healthy breast tissue and DCIS (b6); c6 increased cytoplasmic expression of Zeb1 is evident in IDC. Original magnification× 200

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Cancer Cell International

ISSN: 1475-2867

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