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Fig. 1 | Cancer Cell International

Fig. 1

From: LINC00908 negatively regulates microRNA-483-5p to increase TSPYL5 expression and inhibit the development of prostate cancer

Fig. 1

Low expression of LINC00908 in PCa tissues and cells. a The expression of LINC00908 in PCa-related microarray GSE3325 from the GEO database. b The expression of LINC00908 in PCa-related microarray GSE69223 from the GEO database. c The expression of LINC00908 detected in the GEPIA database. The abscissa represents the sample type and the ordinate represents the expression value; the red box plot represents the tumor sample, and the gray box plot represents the normal sample (* q < 0.01). d The localization of LINC00908 analyzed by the lncATLAS website (http://lncatlas.crg.eu/). e The subcellular localization of LINC00908 in cells detected by FISH assay (× 400). f LINC00908 expression in PCa tissues (n = 55) and paracancerous tissues (n = 55) determined by RT-qPCR, normalized to β-actin, *p < 0.05 vs. paracancerous tissues. g LINC00908 expression in RWPE-1, VCaP, LNCaP, DU-145, and PC-3 cell lines determined by RT-qPCR, normalized to β-actin, *p < 0.05 vs. RWPE-1 cell lines. The above results were measurement data, expressed as mean ± standard deviation, and t-test was used for data comparisons between two groups, while one-way ANOVA and Tukey’s post hoc test were used for comparisons among multiple groups. The cell experiment to measure LINC00908 expression in different cell lines was repeated three times

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